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Recent Publications
Lessard L, Labbé DP, Debloisa G, Bégind LR, Hardya S, ,Mes-Massone AM, Saade F, Trotman LC, Giguère V, Tremblay ML. PTP1B is an androgen receptor-regulated phosphatase associated with tumor-promoting functions in prostate cancer. Cancer Research, OnlineFirst January 26, 2012.
Howitt J, Lackovic J, Low LH, Naguib A, Macintyre A, Goh CP, Callaway JK, Hammond V, Thomas T, Dixon M, Putz U, Silke J, Bartlett P, Yang B, Kumar S, Trotman LC, Tan SS. Ndfip1 regulates nuclear Pten import in vivo to promote neuronal survival following cerebral ischemia. J Cell Biol. 2012 Jan 2.
Chen, M., Pratt, C. P., Zeeman, M. E., Schultz, N., Taylor, B.S., O’Neill, A., Castillo-Martin, M., Nowak, D. G., Naguib, A., Navin, N., Atwal, G.S., Sander C., Gerald W.L., Cordon-Cardo C., Newton A.C., Carver B.S., Trotman L.C. Cancer Cell (2011). Identification of PHLPP1 as a tumor suppressor reveals the role of feedback activation in PTEN-mutant prostate cancer progression. Cancer Cell. 2011 Aug 16;20(2):173-86.
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Reviews
Trotman LC. Calling on the cancer sleuths: how cell biologists will do the detective legwork of the postcancer genome era. Mol Biol Cell. 2011 Mar;22(6):715.PMID: 21406578
Towards patient-based cancer therapeutics. The Cancer Target Discovery and Development Network, Schreiber SL, Shamji AF, Clemons PA, Hon C, Koehler AN, Munoz B, Palmer M, Stern AM, Wagner BK, Powers S, Lowe SW, Guo X, Krasnitz A, Sawey ET, Sordella R, Stein L, Trotman LC, Califano A, Dalla-Favera R, Ferrando A, Iavarone A, Pasqualucci L, Silva J, Stockwell BR, Hahn WC, Chin L, Depinho RA, Boehm JS, Gopal S, Huang A, Root DE, Weir BA, Gerhard DS, Zenklusen JC, Roth MG, White MA, Minna JD, Macmillan JB, Posner BA. Nat Biotechnol. 2010 Sep;28(9):904-906. PMID: 20829823
New views into the prostate cancer genome. Trotman L, Powers S. Cancer Cell. 2010 Jul 13;18(1):1-2. PMID: 20609345
Trotman LC. PTEN. In Ralph A. Bradshaw and Edward A. Dennis, editors: Handbook of Cell Signaling 2nd edition, Oxford:Academic Press, 2009, pp. 849-854.
Lloyd Trotman: of mice and men, cancer, and PTEN. Interviewed by Caitlin Sedwick. Trotman L. J Cell Biol. 2008 May 5;181(3):402-3.
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